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Research Associate

 

Company Overview:

LanzaTech’s award winning technology is revolutionizing the way the world thinks about waste carbon by treating it as an opportunity instead of a liability. LanzaTech has developed proprietary engineered microbes and a novel gas fermentation process that captures and utilizes greenhouse gases  into valuable products as biofuels and chemicals. The company, named one of America’s most promising companies by Forbes Magazine and holds the #2 position and the #4 position in Biofuel’s Digests’ Hot 50 rankings for bioenergy and Hot 30 rankings for renewable chemicals production.

Purpose:

We are seeking a Research Associate to supporting the metabolic engineering of LanzaTech’s proprietary gas fermenting microbes for production of new molecules. The Research Associate will be joining LanzaTech’s Synthetic Biology team and working in a cross-functional project team. Types of activities include plasmid library construction, bacterial transformation and culturing, confirmation of clones and product screening.

Duties & Responsibilities:

  • Design, cloning and assembly of multi-fragment DNA constructs for heterologous pathway expression;
  • Genetic modification and selection of LanzaTech proprietary microbes;
  • High-throughput cultivation, transformation, screening of LanzaTech proprietary microbes;
  • Analysis of growth studies and interpretation of results against model predictions;
  • Use of computational tools and databases;
  • Design experiments in conjunction with scientists across functional groups and support of senior scientist in project;
  • Maintain a laboratory notebook, batch production records and QC data in LIMS system as required;
  • Attend seminars and participate in group and project meetings or lab activities as required.

Requirements:

  • M.Sc. or B.Sc. with at least 2 years of relevant experience in a laboratory setting (or equivalent) in Synthetic Biology, Bioengineering, Biochemistry, Molecular Biology or a related field;
  • Hands-on experience in metabolic engineering, cloning and assembly of DNA and growth of microbes;
  • Use of DNA design software, word processing, data sharing tools, presentation and spreadsheet applications, and familiarity with concepts in statistics and tools to analyze data;
  • Strong organizational, time management, and interpersonal skills;
  • High attention to detail and careful record keeping;
  • Independent and highly self-motivated;
  • Excellent communication skills and the desire to work in a team;
  • Awareness of safety issues in the work environment.

Highly preferred:

  • Experience in biotech industry;
  • Experience with 96-/384-well format experiments;
  • Experience different cloning methods such as Gibson assembly or Golden Gate and genetic tools such as CRISPR;
  • Experience working with genetic and metabolic pathway databases and DNA design software;
  • Experience working with high throughput screening and liquid handling robots and Next Gen sequencing;
  • Experience working with anaerobic microbes;
  • Strong computer literacy, including Office, SharePoint; Experience in scripting and working with large datasets is preferred;
  • Ability to conduct research independently and manage multiple tasks in parallel.

This position is open to candidates authorized to work in the United States on a full-time basis for any employer. LanzaTech is an Equal Employment Opportunity employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, gender, sexual orientation, gender identity or expression, national origin, age, genetic information, disability, or veteran status.

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